SIPA1 Polyclonal Antibody (E-AB-16071)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human cervical cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SIPA1 |
| Synonyms | GTPase activating protein Spa 1, GTPase-activating protein Spa-1, MGC102688, MGC17037, Signal induced proliferation associated 1, Signal induced proliferation associated gene 1, Signal induced proliferation associated protein 1, Signal-induc, p130 SPA-1, p130 SPA1 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm>perinuclear region. Endomembrane system. Mostly localized in the perinuclear membraneous region. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biology, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. |
Other Clones
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Other Formats
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Unconjugated
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