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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human colon cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human SLC4A4
Abbre SLC4A4
Synonyms DKFZp781H1314,  Electrogenic sodium bicarbonate cotransporter 1,  HNBC 1,  HNBC1,  KNBC,  NBC 1,  NBC 2,  NBC1,  NBC2,  NBCE 1,  NBCE1,  Na(+)/HCO3(-) cotransporter,  Na+HCO3- cotransporter 4,  Nbc4,  OTTHUMP00000160355,  OTTHUMP00000218884,  OTTHUMP00000218885,  PNBC,  S,  hhNMC,  kNBC 1,  kNBC1
Swissprot
Cellular Localization Basolateral cell membrane.
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states.
Other Clones

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Unconjugated

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