SLIT2 Polyclonal Antibody (E-AB-13664)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse bladder Verified Samples in IHC: Human liver cancer, Human cervical cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SLIT2 |
| Abbre | SLIT2 |
| Synonyms | Drad 1, E030015M03Rik, E130320P19Rik, FLJ14420, OTTHUMP00000158695, OTTHUMP00000217852, OTTHUMP00000217853, OTTHUMP00000217854, SLI, Slil 3, Slil3, Slit 2, Slit homolog 2, Slit homolog 2 (Drosophila), Slit homolog 2 protein, Slit homolog 2 protein C-product, Slit-2, Slit2 |
| Swissprot | |
| Calculated MW | 170 kDa |
| Cellular Localization | Secreted. The C-terminal cleavage protein is more diffusible than the larger N-terminal protein that is more tightly cell associated. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs. |
Other Clones
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Other Formats
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Unconjugated
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