SNAP25 Polyclonal Antibody (E-AB-14354)
For research use only.
| Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Human brain |
| Dilution | WB 1:500-1:2000, IHC 1:50-200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SNAP25 |
| Abbre | SNAP25 |
| Synonyms | Bdr, CMS18, FLJ23079, HGNC:11132, MGC105414, MGC139754, RIC 4, RIC4, Resistance to inhibitors of cholinesterase 4 homolog, SEC 9, SEC9, SNAP, SNAP 25, SNAP-25, SNAP-25B, SNAP25, SNP 25, SNP25, SUP, Super protein, Synaptosomal associated 25 kDa , bA416N4.2, dJ1068F16.2, sp |
| Swissprot | |
| Calculated MW | 23 kDa |
| Cellular Localization | Cytoplasm>perinuclear region. Cell membrane. Cell junction>synapse>synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs).The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE.For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two.Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release.Two alternative transcript variants encoding different protein isoforms have been described for this gene. |
Other Clones
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Other Formats
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Unconjugated
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