SNX5 Polyclonal Antibody (E-AB-16867)
For research use only.
| Verified Samples |
Verified Samples in WB: K562, Jurkat Verified Samples in IHC: Human lung cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SNX5 |
| Abbre | SNX5 |
| Synonyms | 0910001N05Rik, 1810032P22Rik, AU019504, D2Ertd52e, FLJ10931, OTTHUMP00000030340, OTTHUMP00000062927, OTTMUSP00000003367, OTTMUSP00000003368, RP11-504H3.2, RP23-35E16.2, SNX 5, SNX5, Sorting nexin 5, Sorting nexin-5, snoRNA MBI-43 |
| Swissprot | |
| Calculated MW | 47 kDa |
| Cellular Localization | Early endosome membrane, Cell membrane, Cytoplasmic vesicle membrane, Cytoplasm, Cell projection>phagocytic cup, Cell projection>ruffle, Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3, 4-bisphosphate (PdtIns(3, 4)P2), Detected on macropinosomes, Targeted to membrane ruffles in response to EGFR stimulation. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Other Clones
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Other Formats
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Unconjugated
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