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For research use only.

Verified Samples Verified Samples in IHC: Human brain
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human SOCS2
Abbre SOCS2
Synonyms CIS 2,  CIS-2,  CIS2,  Cish 2,  Cish2,  Cytokine inducible SH2 protein 2,  Cytokine-inducible SH2 protein 2,  SOCS 2,  SOCS-2,  SOCS2,  SSI 2,  SSI-2,  SSI2,  STAT induced STAT inhibitor 2,  STAT-induced STAT inhibitor 2,  STATI 2,  STATI2,  Socs2,  Suppressor of cytokine signaling 2
Swissprot
Cellular Localization Cytosol, Other locations: cytoplasm.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology,  Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.
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Unconjugated

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