SOCS6 Polyclonal Antibody (E-AB-62303)

For research use only.
Verified Samples |
Verified Samples in IHC: Human mammary cancer, Human liver cancer, Human lung cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human SOCS6 (NP_004223.2). |
Abbre | SOCS6 |
Synonyms | CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SOCS6, SSI4, STAI4, STATI4 |
Swissprot | |
Cellular Localization | Cytosol, Plasma Membrane, immunological synapse, Other locations: cytoplasm. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Epigenetics and Nuclear Signaling, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. |
Other Clones
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Other Formats
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Unconjugated
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