SORT1 Polyclonal Antibody (E-AB-13686)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain, Human brain, Human prostate, Human fat, Human placenta Verified Samples in IHC: Human liver cancer, Human breast cancer |
| Dilution | WB 1:500-1:2000, IHC 1:35-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SORT1 |
| Abbre | SORT1 |
| Synonyms | 100 kDa NT receptor, Glycoprotein 95, Gp 95, Gp95, LDLCQ6, NT 3, NT3, NTR 3, NTR3, Neurotensin receptor 3, OTTHUMP00000013784, SORT, SORT 1, SORT1 (gene name), Sort1, Sortilin, Sortilin 1 |
| Swissprot | |
| Calculated MW | 92 kDa |
| Cellular Localization | Membrane. Endoplasmic reticulum membrane. Endosome membrane. Golgi apparatus>Golgi stack membrane. Lysosome membrane. Nucleus membrane. Cell membrane. Lysosome membrane. Localized to membranes of the endoplasmic reticulum, endosomes, Golgi stack, lysosomes and nucleus. A small fraction of the protein is also localized to the plasma membrane. May also be found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes. Localization to the plasma membrane in adipocytes may be enhanced by insulin. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein.The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor.In the TGN, furin mediates the activation of the mature binding form.The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. |
Other Clones
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Other Formats
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Unconjugated
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