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For research use only.

Verified Samples Verified Samples in WB: A375
Verified Samples in IHC: Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human SPARC
Synonyms AA517111,  BM 40,  BM-40,  BM40,  Basement membrane protein 40,  Basement-membrane protein 40,  Cysteine rich protein,  MGC128090,  OI17,  ON,  Osteonectin,  Secreted acidic cystein rich glycoprotein,  Secreted protein acidic ,  Secreted protein acidic and cysteine rich,  hm:zeh0062
Swissprot
Calculated MW 35 kDa
Cellular Localization Secreted>extracellular space>extracellular matrix>basement membrane. In or around the basement membrane.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Cardiovascular,  Developmental Biology,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a cysteine-rich acidic matrix-associated protein.The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape.The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion.
Other Clones

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Unconjugated

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