STK40 Polyclonal Antibody (E-AB-14693)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human lung cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human STK40 |
| Abbre | STK40 |
| Synonyms | 2310004N11Rik, MGC4796, OTTHUMP00000009948, OTTHUMP00000009951, RP11-268J15.4, SHIK, SINK homologous serine/threonine protein kinase, SINK-homologous inhibitory kinase, STK 4, Ser/Thr like kinase, Serine/threonine kinase 40, Serine/threonine protein kinase 40, SgK495 |
| Swissprot | |
| Cellular Localization | Cytoplasmic and Nuclear. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing. |
Other Clones
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Other Formats
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Unconjugated
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