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For research use only.

Verified Samples Verified Samples in WB: Mouse brain
Verified Samples in IHC: Human ovarian cancer
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human STX1A
Abbre STX1A
Synonyms HPC 1,  Neuron specific antigen HPC1,  Neuron-specific antigen HPC-1,  OTTHUMP00000174615,  OTTHUMP00000174616,  OTTHUMP00000174617,  OTTHUMP00000174618,  P35-1,  STX1,  STX1A,  SYN1A,  Syntaxin 1A (brain),  Syntaxin 1A brain,  Syntaxin-1A
Swissprot
Calculated MW 33 kDa
Cellular Localization Secreted and Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Cell junction>synapse>synaptosome.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Clones

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Unconjugated

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