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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human esophagus cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human SYNPO2
Abbre SYNPO2
Synonyms DKFZp686G051,  Genethonin 2,  Genethonin-2,  Myopodin,  SYNP2,  SYNPO 2,  Synaptopodin-2,  Synpo2,  striated muscle specific
Swissprot
Cellular Localization Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. Localizes to the Z-disk in mature striated muscle. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern. partly overlapping with filamentous actin.
Concentration 1.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene.Has an actin-binding and actin-bundling activity.Synaptopodin is a proline-rich, actin-associated protein expressed in mature dendritic spines and renal podocytes.Synaptopodin appears to play a role in the actin-based plasticity of spines by linking actin to the spine apparatus.
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Unconjugated

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