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For research use only.

Verified Samples Verified Samples in WB: RAW264.7
Verified Samples in IHC: Human thyroid cancer, Human thyroid cancer
Dilution WB 1:200-1:1000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human TAB3
Synonyms MAP3K7IP 3,  Mitogen-activated protein kinase kinase kinase 7-interacting protein 3,  NAP1,  NF-kappa-B-activating protein 1,  NFkB activating protein 1,  TAB-3,  TAB3,  TAK1 binding protein 3,  TAK1-binding protein 3,  TGF-beta-activated kinase 1 and MAP3K7-binding p,  Tab3
Swissprot
Calculated MW 79 kDa
Cellular Localization Cytosol, Endosome membrane, Extracellular region or secreted, extracellular exosome, Plasma Membrane.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The product of this gene functions in the NF-kappaB signal transduction pathway.The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1.Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor.The human genome contains a related pseudogene.
Other Clones

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Unconjugated

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