TAB3 Polyclonal Antibody (E-AB-15187)
For research use only.
| Verified Samples |
Verified Samples in WB: RAW264.7 Verified Samples in IHC: Human thyroid cancer, Human thyroid cancer |
| Dilution | WB 1:200-1:1000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human TAB3 |
| Abbre | TAB3 |
| Synonyms | MAP3K7IP 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAB3, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding p, Tab3 |
| Swissprot | |
| Calculated MW | 79 kDa |
| Cellular Localization | Cytosol, Endosome membrane, Extracellular region or secreted, extracellular exosome, Plasma Membrane. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The product of this gene functions in the NF-kappaB signal transduction pathway.The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1.Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor.The human genome contains a related pseudogene. |
Other Clones
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Other Formats
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Unconjugated
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