TAX1BP1 Polyclonal Antibody (E-AB-14418)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human thyroid cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human TAX1BP1 |
Abbre | TAX1BP1 |
Synonyms | 1200003J11Rik, 1700069J21Rik, AA930106, Aa1076, CALCOCO 3, CALCOCO3, D6Ertd404e, D6Ertd772e, Human T cell leukemia virus type 1-binding protein, Liver regeneration-related protein LRRG004, MGC94031, PRO0105, T6BP, Tax1 (human T cell leukemia virus type I) binding prot |
Swissprot | |
Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[ |
Other Clones
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Other Formats
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Unconjugated
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