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For research use only.

Verified Samples Verified Samples in IHC: Human breast carcinoma, Mouse kidney
Dilution IHC 1:50-200
Isotype IgG
Host Mouse
Reactivity Human,  Mouse,  Rat
Applications IHC-p
Clonality Monoclonal
Immunogen Recombinant Protein
Abbre TBP/TATA Binding Protein
Synonyms GTF2D,  GTF2D1,  HDL4,  SCA17,  TATA binding factor,  TATA box binding protein,  TATA box factor,  TATA sequence binding protein,  TATA sequence-binding protein,  TATA-binding factor,  TATA-box factor,  TATA-box-binding protein,  TBP,  TFIID,  Transcription initiation factor TFI
Swissprot
Cellular Localization Nucleus.
Tissue Specificity Widely expressed, with levels highest in the testis and ovary
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Purification Method Protein A purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Clone No. 1F6
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Other Clones

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Unconjugated

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