TBP Monoclonal Antibody (E-AB-22171)

For research use only.
Verified Samples |
Verified Samples in IHC: Human breast carcinoma, Mouse kidney |
Dilution | IHC 1:50-200 |
Isotype | IgG |
Host | Mouse |
Reactivity | Human, Mouse, Rat |
Applications | IHC-p |
Clonality | Monoclonal |
Immunogen | Recombinant Protein |
Abbre | TBP/TATA Binding Protein |
Synonyms | GTF2D, GTF2D1, HDL4, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TFIID, Transcription initiation factor TFI |
Swissprot | |
Cellular Localization | Nucleus. |
Tissue Specificity | Widely expressed, with levels highest in the testis and ovary |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
Purification Method | Protein A purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Clone No. | 1F6 |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. |
Other Clones
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Other Formats
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Unconjugated
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