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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human TERF2
Abbre TERF2
Synonyms TERF 2,  TERF2,  TRBF 2,  TRBF2,  TRF 2,  TRF2,  TTAGGG repeat binding factor 2,  TTAGGG repeat-bind,  Telomeric DNA binding protein,  Telomeric DNA-binding protein,  Telomeric repeat binding factor 2,  Telomeric repeat binding protein 2,  Telomeric repeat-binding factor 2,  Terf2
Swissprot
Cellular Localization Nucleus. Chromosome>telomere. Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
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Unconjugated

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