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For research use only.

Verified Samples Verified Samples in WB: Mouse spleen, Human fetal liver, Hela, Mouse testis, A431
Verified Samples in IHC: Human lung cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human THOC7
Abbre THOC7
Synonyms FLJ23445,  Functional spliceosome associated protein 24,  Functional spliceosome-associated protein 24,  Ngg1 interacting factor 3 like 1 binding protein 1,  Ngg1 interacting factor 3 like protein 1 binding protein 1,  Ngg1-interacting factor 3-like ,  fSAP24,  hTREX30
Swissprot
Calculated MW 24 kDa
Cellular Localization Cytoplasm. Nucleus. Interaction with THOC5 is required for nuclear localization.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1.NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors.The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.
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Unconjugated

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