TIMM8A Polyclonal Antibody (E-AB-52670)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer |
| Dilution | IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TIMM8A |
| Abbre | TIMM8A |
| Synonyms | DDP, DDP 1, DDP1, DFN 1, DFN1, Deafness dystonia protein 1, Deafness/dystonia peptide, MGC12262, MTS, Mitochondrial import inner membrane translocase subunit Tim8 A, TIM 8A, TIM8, TIM8A, TIMM 8A, Translocase of inner mitochondrial membrane 8 homolog A, X li, timm8a |
| Swissprot | |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 1.62 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Other Clones
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Unconjugated
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