TIRAP Polyclonal Antibody (E-AB-17096)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human thyroid cancer |
| Dilution | IHC 1:25-100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | TIRAP |
| Synonyms | Adapter protein wyatt, FLJ42305, MAL, MyD88 adapter like protein, TIR domain containing adapter protein, Toll interleukin 1 receptor (TIR) domain containing adaptor protein, Toll interleukin 1 receptor domain containing adapter protein, Toll like receptor adapto |
| Swissprot | |
| Cellular Localization | Cytoplasmic |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns.Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction.The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system.It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response.Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. |
Other Clones
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Other Formats
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Unconjugated
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