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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human TNFRSF8
Abbre TNFRSF8
Synonyms CD 30,  CD30,  CD30 antigen,  CD30L receptor,  Cytokine receptor CD30,  D1S166E,  KI 1,  KI 1 antigen,  KI1,  Ki-1 antigen,  Lymphocyte activation antigen CD30,  TNFRSF 8,  TNR8,  Tnfrsf8,  Tumor necrosis factor receptor superfamily member 8
Swissprot
Cellular Localization Cytoplasm and Cell membrane.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Other Clones

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Unconjugated

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