TPM1 Polyclonal Antibody (E-AB-10661)

For research use only.
Verified Samples |
Verified Samples in WB: Mouse heart, Mouse muscle Verified Samples in IHC: Human gastric cancer, Human breast cancer |
Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human TPM1 |
Abbre | TPM1 |
Synonyms | AA986836, AI854628, Alpha tropomyosin, Alpha-tropomyosin, C15orf13, CMD1Y, CMH3, HTM alpha, HTM-alpha, OTTHUMP00000163688, TM2, TMSA, TPM1, Tmpa, Tpm-1, alpha-TM, cardiomyopathy, hypertrophic 3, sarcomeric tropomyosin kappa, tropomyosin 1 (alpha), tropomyosin 1 (alpha) |
Swissprot | |
Calculated MW | 33 kDa |
Cellular Localization | Cytoplasm>cytoskeleton. |
Concentration | 0.1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells.Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil.It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments.The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described.Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. |
Other Clones
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Other Formats
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Unconjugated
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