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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human TRIP4
Synonyms ASC 1,  ASC-1,  Activating signal cointegrator 1,  HsT17391,  TR-interacting protein 4,  TRIP 4,  TRIP-4,  TRIP4,  Thyroid hormone receptor interactor 4,  Thyroid receptor interacting protein 4,  Thyroid receptor-interacting protein 4,  Trip4,  ZC2HC5,  Zinc finger C2HC5 type
Swissprot
Cellular Localization Nucleus. Cytoplasm. Cytoplasmic under conditions of serum deprivation.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Activating signal co-integrator-1 (ASC-1), originally identified as TRIP4, is a transcriptional co-activator of nuclear receptors that associates with specific components of the RNA polymerase II complex and binds the basal transcription factors TBP and TFIIA.ASC-1 functions with the transcription integrators SRC-1 and CBP/p300 through its zinc finger motif and is dependent on their ligand-dependent transactivation domain, AF2.Endogenous ASC-1 in HeLa cells is predominantly a nuclear protein.Under conditions of serum starvation, ASC-1 localizes to the cytoplasm.
Other Clones

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Unconjugated

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