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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer
Dilution IHC 1:30-150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human UACA
Abbre UACA
Synonyms FLJ10128,  KIAA1561,  MGC141967,  MGC141969,  NUCLING,  Nuclear membrane binding protein,  UACA,  Uveal autoantigen with coiled coil domains and ankyrin repeats,  Uveal autoantigen with coiled-coil domains and ankyrin repeats
Swissprot
Cellular Localization Nucleus. Cytoplasm. Cytoplasm>cytoskeleton. Expressed diffusely in cytoplasm.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell biology,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
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Unconjugated

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