UBP1 Polyclonal Antibody (E-AB-16563)
For research use only.
| Verified Samples |
Verified Samples in WB: PC-3 Verified Samples in IHC: Human cervical cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human UBP1 |
| Abbre | UBP1 |
| Synonyms | LBP-1B, LBP-1a, LBP1A, LBP1B |
| Swissprot | |
| Calculated MW | 60 kDa |
| Cellular Localization | Cytosol, Nucleus, nucleoplasm, nucleus. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family).LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells.LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region.Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis. |
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Unconjugated
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