Uncoated Human PD-L1 (Programmed Cell Death Protein 1 Ligand 1) ELISA Kit (E-UNEL-H0341)
Product Summary
The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.
| Detection Range | 0.16-10 ng/mL |
| Sample Volume | 100 μL |
| Total Assay Time | 24 h |
| Reactivity | Human |
| Specificity | This kit recognizes Human PD-L1 in samples.No significant cross-reactivity or interference between Human PD-L1 and analogues was observed |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T*5 / 96T*15 |
| Storage | -20℃ |
| Expiration Date | 12 months |
Background
Programmed cell death ligand 1(CD274,or B7-H1,PD-L1),is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors,the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell,and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal,essential for T-cell proliferation and production of IL10 and IFNG,in an IL2-dependent and a PDCD1-independent manner. PD-L1 is a 290 aa transmembrane protein with a calculated molecular weight of 33 kDa,the apparent molecular weight has been reported as 45-70 kDa,suggesting probable glycosylation .
| Gene ID | 29126 |
| Uniport ID | Q9NZQ7 |
| Research Area | Cancer , Immunology |
| Cat.No. | Product Name | Clone No. |
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