Uncoated Mouse RANκL (Receptor Activator of Nuclear Factor Kappa B Ligand) ELISA Kit (E-UNEL-M0125)
Product Summary
The new series of Elabscience® Uncoated ELISA kits contain the basic components required for the ELISA experiments. For customers who have rich experience and can establish their own ELISA system, uncoated kit is an ideal choice to save costs.
| Detection Range | 31.25-2000 pg/mL |
| Sample Volume | 100 μL |
| Total Assay Time | 24 h |
| Reactivity | Mouse |
| Specificity | This kit recognizes Mouse RANκL in samples.No significant cross-reactivity or interference between Mouse RANκL and analogues was observed |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T*5 / 96T*15 |
| Storage | -20℃ |
| Expiration Date | 12 months |
Background
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor.Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells; chief among which is induction of long lasting oscillations in the intracellular concentration of Ca 2+ resulting in the activation of NFATC1; which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts.
| Gene ID | 21943 |
| Uniport ID | O35235 |
| Research Area | Cancer , Cardiovascular , Immunology |
| Cat.No. | Product Name | Clone No. |
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