VCAM1/VCAM-1/CD106 Monoclonal Antibody (AN200166P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human tonsil, Human spleen, Human kidney |
| Dilution | IHC-P 1:200-1:2000 |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human VCAM1/VCAM-1/CD106 Protein |
| Abbre | VCAM1 |
| Synonyms | MGC, Vascular cell adhesion protein, Vascular Cell Adhesion Molecule, V-CAM, CD106, INCAM-100, VCAM1, CD106 Antigen, INCAM 100, L1CAM, MGC99561, Vascular Cell Adhesion Molecule 1, VCAM 1, VCAM-1, Vascular cell adhesion protein 1, V-CAM 1, INCAM-110, V-CAM |
| Swissprot | |
| Cellular Localization | Membrane |
| Tissue Specificity | Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Signal Transduction, Neuroscience, Stem Cells, Cancer, Cardiovascular, Kits, Lysates, Other |
| Clone No. | 5A8 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
Other Clones
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Unconjugated
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