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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human CDH5
Abbre CDH5
Synonyms 1,  7B 4,  7B4,  7B4 antigen,  CADH5,  CD 144,  CD144,  CD144 anti,  Cadherin 5,  Cadherin 5 type 2,  Cadherin-5,  Cadherin5,  VE cadherin (vascular epithelium),  cadherin,  type 2,  type 2 (vascular endothelium),  vascular endothelial
Swissprot
Cellular Localization Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Other Clones

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Unconjugated

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