VPS45 Polyclonal Antibody (E-AB-17268)
For research use only.
Verified Samples |
Verified Samples in IHC: Human liver cancer |
Dilution | IHC 1:30-150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human VPS45 |
Abbre | VPS45 |
Synonyms | H1, H1VPS45, HGNC:14579, Leucocyte vacuolar protein sorting 45, OTTHUMP00000014482, Vacuolar protein sorting 45 homolog (S. cerevisiae), Vacuolar protein sorting 45A, Vacuolar protein sorting 45A (yeast homolog), Vacuolar protein sorting 45B (yeas, h-VPS45, hlVps45 |
Swissprot | |
Cellular Localization | Golgi apparatus membrane. Endosome membrane. Associated with Golgi/endosomal vesicles and the trans-Golgi network. |
Concentration | 1.1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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