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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer
Dilution IHC 1:30-150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human VPS45
Abbre VPS45
Synonyms H1,  H1VPS45,  HGNC:14579,  Leucocyte vacuolar protein sorting 45,  OTTHUMP00000014482,  Vacuolar protein sorting 45 homolog (S. cerevisiae),  Vacuolar protein sorting 45A,  Vacuolar protein sorting 45A (yeast homolog),  Vacuolar protein sorting 45B (yeas,  h-VPS45,  hlVps45
Swissprot
Cellular Localization Golgi apparatus membrane. Endosome membrane. Associated with Golgi/endosomal vesicles and the trans-Golgi network.
Concentration 1.1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene.
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Unconjugated

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