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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human colon cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human WDR83
Abbre WDR83
Synonyms MAPK organizer 1,  MGC4238,  MORG 1,  Mitogen activated protein kinase organizer 1>,  Mitogen-activated protein kinase organizer 1,  WD repeat domain-containing protein 83,  WDR83,  wdr83
Swissprot
Cellular Localization Cytoplasm. Nucleus. Predominantly cytoplasmic (By similarity). Partially nuclear.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Epigenetics and Nuclear Signaling,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.
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Unconjugated

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