WDR83 Polyclonal Antibody (E-AB-15188)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human colon cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human WDR83 |
| Abbre | WDR83 |
| Synonyms | MAPK organizer 1, MGC4238, MORG 1, Mitogen activated protein kinase organizer 1>, Mitogen-activated protein kinase organizer 1, WD repeat domain-containing protein 83, WDR83, wdr83 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Predominantly cytoplasmic (By similarity). Partially nuclear. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. |
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