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Discovery of Novel Covalent Agonists for p53 Y220C through Synergistic Strategy Combining Covalent Binding and Scaffold Hopping
IF: 5.900
  • Journal: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY(2026)
  • DOI: 10.1016/j.ejmech.2026.118801
  • Products: HuH-6 Cells Line, HuH-7 Cells Line
  • Product Category: Cell Lines
Melatonin alleviates airway inflammation and anxiety-depression in asthma via gut microbiota–SCFA axis-mediated inhibition of microglial activation
IF: 5.900
Recombinant human adenovirus type 5 synergizes with anti-PD-L1 antibody to promote anti-hepatocellular carcinoma effects through multilevel remodeling of the immune microenvironment
IF: 5.900
Inosine alleviates colorectal cancer liver metastasis by promoting M1 macrophage polarization and modulating the PI3K/AKT signaling pathway
IF: 5.900
  • Journal: Frontiers in Immunology(2026)
  • DOI: 10.3389/fimmu.2026.1780972
  • Products: RAW 264.7 Cells Line, CCD-841 Cell Lines, MC38 Cells Line
  • Product Category: Cell Lines
In vitro oogenesis and parthenogenetic development of chicken female germ cells
IF: 5.900
CPEB1 drives ferroptosis–neuroinflammation crosstalk in temporal lobe epilepsy via the SIRT1–NRF2 acetylation axis
IF: 5.900
Exploring the potential mechanisms of PFDoA-induced microglial pyroptosis using cell biology experiments, network toxicology and molecular docking
IF: 5.900
Synergistic Modification of β-Casein Micelles by Dextran and Genipin for Naringenin Delivery: A Systematic Evaluation of Physicochemical Stability, Digestive Properities, and Cellular Uptake
IF: 5.900
Biological activities, metabolic profiles, and in vitro uric acid-lowering mechanisms of cell-free supernatant from coconut water by Limosilactobacillus DO28L8
IF: 5.900
Immunomodulatory potential of Lactiplantibacillus pentosus LIHUO 03: Insights from the gut-metabolism-immune axis in cyclophosphamide-induced immunosuppressed mice
IF: 5.900
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