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Human collagen type I α2(COL1α2) and collagen type I α1(COL1α1), can the two be distinguished and can cross-reaction occur?

Source: Elabscience® Published: Oct 19,2021 Updated: Oct 19,2021

Collagen (COL1) consists of three peptide chains, two of which are α(Ⅰ) chain, COL1α1, and one α(Ⅱ) chain, col1α2. The homology between the two was 60.396%, and there was no obvious cross-reaction.