ELISA Research
What is the difference between PGD2 and PGE2?
Source: Elabscience®Published: Mar 08,2024
These two belong to different types of prostaglandins.
Prostaglandin E2 (PGE2) is the most abundant prostaglandin and is produced by the action of prostaglandin E synthetase on prostaglandin H2(PGH2).
Prostaglandin D2(PGD2) is another prostaglandin produced by hematopoietic and lipoprotein prostaglandin D synthase (hPGDS and lPGDS) acting on prostaglandin H2(PGH2).
In addition, the two have different receptors and different areas of study.
PGE2: Mainly studies gastrointestinal smooth muscle
PGD2: Studies allergic diseases such as asthma