Elab Fluor® 488 Anti-Human CD16 Antibody[3G8] (E-AB-F1236L)
![Elab Fluor<sup>®</sup> 488 Anti-Human CD16 Antibody[3G8] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Elab Fluor®488
APC Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 540 Elab Fluor®Violet 610 FITC None (AF/LE) PE PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human, Rhesus, Cynomolgus |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD16 |
| Synonyms | Fc gamma receptor, Fc gamma receptor 3, FcγRIII |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Innate Immunity |
| Clone No. | 3G8 |
| Conjugation | Elab Fluor®488 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
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