APC Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] (E-AB-F1016UE)
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For research use only.
| Alternate Names | Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47 |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking. |
| Abbre | CD47 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human;Mouse;Rat |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1, κ |
| Isotype Control | APC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology;Innate Immunity |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
0.2 mg/mL
|
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
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