Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> Biotin Anti-Human CD57 Antibody[HNK-1] E-AB-F1067B
Cat.No.:E-AB-F1067B
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Alternate Names | HNK-1, NK-1, Leu-7 |
References |
1. Schubert J, et al. 1989. In Leucocyte Typing IV (Knapp W, ed) Oxford University Press Oxford pp 711-714.
2. Palmer BE, et al. 2005. J. Immunol. 175:8415. 3. Schachner M, et al. 1995. Trends Neurosci. 18:183. 4. Wood KL, et al. 2005. Clin. Immunol. 117:294. |
Form | Liquid |
Clone No. | HNK-1(See Other Available Formats) |
Host | Mouse |
Isotype | Mouse IgM, κ |
Isotype Control | Biotin Mouse IgM, κ Isotype Control[MM-30] [Product E-AB-F09783B] |
Reactivity | Human |
Application | FCM (See the Application Description) |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | Biotin |
How to select the appropriate detection channel through the spectrogram?
CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
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