FITC Anti-Human CD45RO Antibody[UCHL1] (E-AB-F1139C)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

Cell Markers

Size	Price	Qty
100Tests	$ 60.00	- +
20Tests	$ 21.00	- +
100Tests×2	$ 100.00	- +

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Conjugation: FITC

Isotype	Mouse IgG2a, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Abbre	CD45RO
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers, Stem Cells
Clone No.	UCHL1
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.