FITC Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] (E-AB-F1112C)
For research use only.
| Alternate Names | B220 |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas<sup>lpr</sup> and MRL-Fas<sup>gld</sup> mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| Abbre | CD45R |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgM, κ |
| Isotype Control | E-AB-F09772C |
| Applications |
FCM
|
| Research Areas | Cell Biology;Immunology;Inhibitory Molecules;Neuroscience;Neuroscience Cell Markers |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | FITC |
| Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
Elab Fluor®Violet 540
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP
PerCP/Cyanine 5.5
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