Alternate Names	High affinity immunoglobulin epsilon receptor subunit alpha,Fc-epsilon RI-alpha,FcERI,Fcer1a
Swissprot	P20489
References	1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105. 2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.

Product Details

Form	Liquid
Clone No.	MAR-1(See Other Available Formats)
Host	Armenian Hamster
Isotype	Armenian Hamster IgG
Isotype Control	FITC Armenian Hamster IgG Isotype Control[PIP] [Product E-AB-F09852C]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	FITC
	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
PE Anti-Mouse FcεRIα Antibody[MAR-1]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse FcεRIα Antibody[MAR-1]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse FcεRIα Antibody[MAR-1]	25μg, 100μg	Check More
PE Anti-Mouse FcεRIα Antibody[MAR-1]	25μg, 100μg	Check More
APC Anti-Mouse FcεRIα Antibody[MAR-1]	25μg, 100μg	Check More

Citations

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