Purified Mouse FcεRIα Antibody[MAR-1] (E-AB-F1188A)
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FCM Related Reagents
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For research use only.
| Alternate Names | Fc-epsilon RI-alpha, Fce1a, fcepsilonri, Fcer1a, FcERI, Fcr, Fcr-5, High affinity immunoglobulin epsilon receptor subunit alpha |
| Clone | |
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse bone marrow |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit. |
| Immunogen | Recombinant Mouse FcεRIα protein |
| Abbre | FcεRIα |
| Swissprot | |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Armenian Hamster IgG |
| Isotype Control | Purified Armenian Hamster IgG Isotype Control[PIP] |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN012180P | Purified Anti-Mouse FcεRIα Antibody[E10641] | E10641 |
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