Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> PE Anti-Mouse CD115 Antibody[AFS98] E-AB-F1107UD
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|Alternate Names||Macrophage colony-stimulating factor 1 receptor,CSF-1 receptor (EC:126.96.36.199),CSF-1-R,CSF-1R,M-CSF-R,Proto-oncogene c-Fms,CD115,Csf1r,Csfmr,Fms|
1. Sudo T, et al. 1995 Oncogene 11:2469.
2. Murayama T, et al. 1999 Circulation 99:1740.
3. Goswami S, et al. 2005 Cancer Res. 65:5278.
4. Yu W, et al. 2008 J. Leuko. Biol. 84:852.
|Clone No.||AFS98(See Other Available Formats)|
|Isotype||Rat IgG2a, κ|
|Isotype Control||PE Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833D]|
|Application||FCM (See the Application Description)|
|Storage Buffer||Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.|
|Recommended Use||Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).|
How to select the appropriate detection channel through the spectrogram?
|CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|AF/LE Purified Anti-Mouse CD115 Antibody[AFS98] E-AB-F11070||50μg, 500μg, 1mg||Check More|
|Purified Anti-Mouse CD115 Antibody[AFS98] E-AB-F1107A||25μg, 100μg||Check More|
|PE Anti-Mouse CD115 Antibody[AFS98] E-AB-F1107D||50Tests, 100Tests, 100Tests×2||Check More|
|APC Anti-Mouse CD115 Antibody[AFS98] E-AB-F1107E||50Tests, 100Tests, 100Tests×2||Check More|
|APC Anti-Mouse CD115 Antibody[AFS98] E-AB-F1107UE||25μg, 100μg||Check More|
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