Elab Fluor®488 Anti-Mouse CD115/CSF-1R Antibody[AFS98] (E-AB-F1107L)
For research use only.
Conjugation: Elab Fluor®488
APC Elab Fluor®488 Elab Fluor®700 PE PerCP/Cyanine 5.5 Unconjugated Show More
| Alternate Names | Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, Csf1r, Csfmr, Fms |
| Clone | |
| Background | CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts. |
| Abbre | CD115/CSF-1R |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Elab Fluor® 488 Rat IgG2a, κ Isotype Control[2A3] |
| Applications |
FCM
|
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | Elab Fluor®488 |
| Conjugation Information | Elab Fluor®488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
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