Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152H

PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152H

Uniprot : P16871

Cat.No.:E-AB-F1152H
Reactivity: Human

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Antigen Details

Alternate Names	Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα
Swissprot	P16871
References	1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125. 2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503. 3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610. 4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403. 5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707. 6. Liu W, et al. 2006. J. Exp. Med. 203:1701.

Product Details

Form	Liquid
Clone No.	A019D5(See Other Available Formats)
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792H]
Reactivity	Human
Application	FCM (See the Application Description)
Storage Buffer	PBS with 0.05% Proclin300, 1% BSA
Recommended Use	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	PE/Cyanine7

Background

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No.	Product Name	Sizes
E-AB-F1152C	FITC Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152C	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152D	PE Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152D	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152E	APC Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152E	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152G	PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152G	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152H	PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152H	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152I
E-AB-F1152J	PerCP/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152J	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152L	AF488 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152L	20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152M	AF647 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152M	20 Tests, 50 Tests, 100 Tests, 200 Tests

Citations

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