Current Position:Home>>Antibodies>>FCM Antibodies>> PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133H
|Alternate Names||B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1|
1. Sharpe A, et al. 2007. Nat. Immunol. 8:239.
|Clone No.||29E.2A3(See Other Available Formats)|
|Isotype||Mouse IgG2b, κ|
|Isotype Control||PE/Cyanine7 Mouse IgG2b, κ Isotype Control[MPC-11] [Product E-AB-F09812H]|
|Application||FCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|E-AB-F11330||AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F11330||50 μg, 500 μg, 1 mg|
|E-AB-F1133A||Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133A||25 μg, 100 μg|
|E-AB-F1133B||Biotin Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133B||25 μg, 100 μg|
|E-AB-F1133C||FITC Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133C||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1133D||PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133D||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1133E||APC Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133E||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1133G||PE/Cyanine5 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133G||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1133H||PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133H||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1133J||PerCP/Cyanine5.5 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133J||20 Tests, 50 Tests, 100 Tests, 200 Tests|