PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133H

Uniprot : Q9NZQ7
  • Host: Mouse
  • Applications: FCM
  • Isotype: Mouse IgG2b, κ

To Purchase E-AB-F1133H

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Antigen Details

Alternate Names B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Swissprot Q9NZQ7
References
1. Sharpe A, et al. 2007. Nat. Immunol. 8:239.

Product Details

Form Liquid
Clone No. 29E.2A3(See Other Available Formats)
Host Mouse
Isotype Mouse IgG2b, κ
Isotype Control PE/Cyanine7 Mouse IgG2b, κ Isotype Control[MPC-11] [Product E-AB-F09812H]
Reactivity Human
Application FCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation PE/Cyanine7

Background

CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F11330 AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F11330 50 μg, 500 μg, 1 mg
E-AB-F1133A Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133A 25 μg, 100 μg
E-AB-F1133B Biotin Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133B 25 μg, 100 μg
E-AB-F1133C FITC Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133C 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1133D PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1133E APC Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133E 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1133G PE/Cyanine5 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133G 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1133H PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133H 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1133J PerCP/Cyanine5.5 Anti-Human CD274/PD-L1 Antibody[29E.2A3] E-AB-F1133J 20 Tests, 50 Tests, 100 Tests, 200 Tests

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