PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] (E-AB-F1112UH)
![PE/Cyanine7 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: PE/Cyanine 7
APC Biotin Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 Elab Fluor®Violet 540 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Rat IgM, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD45R/B220 |
| Synonyms | B220 |
| Cellular Localization | Membrane |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers |
| Clone No. | RA3.3A 1/6.1 |
| Conjugation | PE/Cyanine 7 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas<sup>lpr</sup> and MRL-Fas<sup>gld</sup> mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN00428UH | PE/Cyanine7 Anti-Mouse CD45R (B220) Antibody[RA3-6B2] | RA3-6B2 |
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