Alternate Names	Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117
Swissprot	P05532
References	1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Galli SJ, et al. 1994. Adv. Immunol. 55:1. 3. Ikuta K, et al. 1992. Annu. Rev. Immunol. 10:759. 4. Besmer P, et al. 1986. Nature 320:415. 5. Witte ON. 1990. Cell 63:5.

Product Details

Form	Liquid
Clone No.	2B8(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2b, κ
Isotype Control	Purified Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843A]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Unconjugated

How to select the appropriate detection channel through the spectrogram?

Background

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD117/c-Kit Antibody[2B8]	50μg, 500μg, 1mg	Check More
Biotin Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More
FITC Anti-Mouse CD117/c-Kit Antibody[2B8]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD117/c-Kit Antibody[2B8]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD117/c-Kit Antibody[2B8]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD117/c-Kit Antibody[2B8]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Mouse CD117/c-Kit Antibody[2B8]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Mouse CD117/c-Kit Antibody[2B8]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More
PE Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More
APC Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More
Elab Fluor^® 488 Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More
Elab Fluor^® 647 Anti-Mouse CD117/c-Kit Antibody[2B8]	25μg, 100μg	Check More

Citations

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