Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173] E-AB-F1114A
Cat.No.:E-AB-F1114A
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Alternate Names | C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183 |
Swissprot | O88410 |
References |
1. Krug A, Uppaluri R, Facchetti F, et al. J Immunol. 2002; 169(11):6079-6083.
2. Soto H, Wang W, Strieter RM, et al. Proc Natl Acad Sci U S A. 1998; 95(14):8205-8210. 3. Tamaru M, Tominaga Y, Yatsunami K, Narumi S. Biochem Biophys Res Commun. 1998; 251(1):41-48. |
Form | Liquid |
Clone No. | CXCR3-173(See Other Available Formats) |
Host | Armenian Hamster |
Isotype | Armenian Hamster IgG |
Isotype Control | Purified Armenian Hamster IgG Isotype Control[PIP] [Product E-AB-F09853A] |
Reactivity | Mouse |
Application | FCM (See the Application Description) |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | Unconjugated |
How to select the appropriate detection channel through the spectrogram?
CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
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