Purified Anti-Mouse CD209b Antibody[22D1] (E-AB-F1022A)
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For research use only.
| Alternate Names | OtB, DC-SIGN-related protein, DC-SIGNR, CD209, CD209 antigen-like protein B, DC-SIGNR1, DC-SIGN-related protein 1, OtB7, Cd209b |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Verified Samples | Verified Samples in FCM: Mouse peritoneal macrophages |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. |
| Immunogen | Recombinant Mouse CD209b protein |
| Abbre | CD209b |
| Swissprot | |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Armenian Hamster IgG |
| Isotype Control | Purified Armenian Hamster IgG Isotype Control[PIP] |
| Applications |
FCM
|
| Cellular Localization |
Membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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