Alternate Names	Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
Swissprot	P27512
References	1. Hasbold J, Johnson-Leger C, Atkins CJ, Clark EA, Klaus GG. Eur J Immunol. 1994; 24(8):1835-1842. 2. Hasbold J, Klaus GG. Eur J Immunol. 1994; 24(1):152-157. 3. Klaus GG, Holman M, Hasbold J. Eur J Immunol. 1994; 24(11):2714-2719. 4. Noelle RJ, Ledbetter JA, Aruffo A. Immunol Today. 1992; 13(11):431-433. 5. Parry SL, Hasbold J, Holman M, Klaus GG. J Immunol. 1994; 152(6):2821-2829.

Product Details

Form	Liquid
Clone No.	FGK4.5/FGK45(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2a, κ
Isotype Control	Purified Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833A]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Unconjugated

How to select the appropriate detection channel through the spectrogram?

Background

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50μg, 500μg, 1mg	Check More
Biotin Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
FITC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5.5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
PE/Elab Fluor^® 594 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
PE Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
APC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
PE/Cyanine5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
PE/Cyanine5.5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
PerCP/Cyanine5.5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
Elab Fluor^® 488 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
Elab Fluor^® 647 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More
PE/Elab Fluor^® 594 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]	25μg, 100μg	Check More

Citations

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