PE/Cyanine5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45] (E-AB-F1028UG)
![PE/Cyanine5 Anti-Mouse CD40 Antibody[FGK4.5/FGK45] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: PE/Cyanine 5
APC Biotin Elab Fluor®488 Elab Fluor®647 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD40 |
| Synonyms | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers |
| Clone No. | FGK4.5/FGK45 |
| Conjugation | PE/Cyanine 5 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
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